BDBM1869 3-methyl-1-(2-phenylethyl)-3-1,3-thiazol-2-ylthiourea::PETT Analog 36

SMILES CN(C(=S)NCCc1ccccc1)c1nccs1

InChI Key InChIKey=SZLHGPJAYQWUEP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 1869   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM1869(3-methyl-1-(2-phenylethyl)-3-1,3-thiazol-2-ylthiou...)
Affinity DataIC50: 1.50E+3nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2004
Entry Details Article
PubMed