BDBM187331 BDBM187332::US9169240, 70

SMILES CN1CCC(Nc2nnc(o2)C(=O)c2nc3ccc(cc3s2)-c2ccccc2)C1=O

InChI Key InChIKey=QTMQGCKSVSPKHX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 187331   

TargetEndothelial lipase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM187331(US9169240, 70 | BDBM187332)
Affinity DataIC50: 22nMpH: 8.0Assay Description:The enzymatic assay was measured using white, opaque 96-well half area plates. Each well contained 60 μL of assay buffer (50 mM HEPES pH 8.0, 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetEndothelial lipase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM187331(US9169240, 70 | BDBM187332)
Affinity DataIC50: 190nMpH: 8.0Assay Description:The enzymatic assay was measured using white, opaque 96-well half area plates. Each well contained 60 μL of assay buffer (50 mM HEPES pH 8.0, 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent