BDBM188368 US9169224, 52

SMILES FC1(F)Oc2ccc(CN3CCN(CC3)C(=O)Nc3ccccc3)cc2O1

InChI Key InChIKey=LWANTKLMGLEVHN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 188368   

TargetFatty-acid amide hydrolase 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM188368(US9169224, 52)
Affinity DataIC50: 87nMpH: 9.0Assay Description:Assay Method 1: T84 frozen pellets (contents of 1-4x15 cm culture dishes) were homogenized in 300 mL of FAAH assay buffer (125 mM Tris, 1 mM EDTA, 0....More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM188368(US9169224, 52)
Affinity DataIC50: 100nMpH: 9.0Assay Description:T84 frozen cell pellets or transfected SK-N-MC cells (contents of 1x15 cm culture dishes) were homogenized in 50 mL of FAAH assay buffer (125 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM188368(US9169224, 52)
Affinity DataIC50: 290nMpH: 9.0Assay Description:T84 frozen cell pellets or transfected SK-N-MC cells (contents of 1x15 cm culture dishes) were homogenized in 50 mL of FAAH assay buffer (125 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
Go to US Patent