BDBM188475 US9670194, Ex. 23 (S)-2-(1-((6-amino-5-(3-methyl-1,2,4-oxadiazol-5-yl)pyrimidin-4-yl)amino)-propyl)-3-cyclopropyl-5-fluoroquinazolin-4(3H)-one

SMILES CC[C@H](Nc1ncnc(N)c1-c1nc(C)no1)c1nc2cccc(F)c2c(=O)n1C1CC1

InChI Key InChIKey=GAELXURZTAIMHJ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 188475   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta/delta isoform(Human)
Calitor Sciences

US Patent

LigandBDBM188475(US9670194, Ex. 23 (S)-2-(1-((6-amino-5-(3-methyl-1...)Copy SMILESCopy InChI

Affinity DataIC50: 52nMT: 2°CAssay Description:PI3K (p110α/p85α) (h) is incubated in assay buffer containing 10 μM phosphatidylinositol 4,5-bisphosphate and MgATP (concentration as ...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
5/19/2018
Entry Details
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