BDBM1886 3-(5-methylpyridin-2-yl)-1-(2-phenylethyl)thiourea::N-(2-Phenethyl)-N -(2-(5-methylpyridyl))thiourea::PETT Analog 53::cid_971434

SMILES Cc1ccc(NC(=S)NCCc2ccccc2)nc1

InChI Key InChIKey=FTLVKPIQAUANGB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 1886   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM1886(N-(2-Phenethyl)-N -(2-(5-methylpyridyl))thiourea |...)
Affinity DataIC50: 30nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2004
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM1886(N-(2-Phenethyl)-N -(2-(5-methylpyridyl))thiourea |...)
Affinity DataIC50: 5.50E+3nMpH: 7.4 T: 2°CAssay Description:Factor XIa (0.23 ug/mL) was incubated with Boc-Glu-Ala-Arg-AMC substrate (15 uM) in 10 uL of assay buffer for 2 hr at room temperature. Read fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2009
Entry Details
PCBioAssay