BDBM189858 US9670196, 1.3 1,1,1-trifluoro-2-{5-[3- methyl-5-(thieno[3,2- d]pyrimidin-4- ylamino)phenyl]-1,3- thiazol-2-yl}propan-2-ol

SMILES Cc1cc(Nc2ncnc3ccsc23)cc(c1)-c1cnc(s1)[C@](C)(O)C(F)(F)F

InChI Key InChIKey=YTJMMABMYSLKFV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 189858   

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM189858(US9670196, 1.3 1,1,1-trifluoro-2-{5-[3- methyl-5-(...)
Affinity DataIC50: 5.82E+3nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
Go to US Patent