BDBM19017 N-{4-[1-(4-methoxyphenyl)-7-oxo-3-(trifluoromethyl)-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridin-6-yl]phenyl}-N-methylacetamide::trifluoromethylpyrazole analogue, 36d

SMILES COc1ccc(cc1)-n1nc(c2CCN(C(=O)c12)c1ccc(cc1)N(C)C(C)=O)C(F)(F)F

InChI Key InChIKey=JEEDSFZNOOUNBM-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 19017   

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM19017(N-{4-[1-(4-methoxyphenyl)-7-oxo-3-(trifluoromethyl...)
Affinity DataKi:  0.5nMAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2007
Entry Details Article
PubMed
TargetProthrombin(Human)
Bristol-Myers Squibb

LigandPNGBDBM19017(N-{4-[1-(4-methoxyphenyl)-7-oxo-3-(trifluoromethyl...)
Affinity DataKi: >6.30E+3nMAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2007
Entry Details Article
PubMed