BDBM190276 US9180116, 28D::US9180116, 28G

SMILES C[C@@H](CCCc1ccccc1)[C@@H](O)\C=C\[C@H]1CC(F)(F)C(=O)N1CCCc1ccc(s1)C(O)=O

InChI Key InChIKey=UXQWNSWYEJSWBM-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 190276   

TargetProstaglandin E2 receptor EP4 subtype(Human)
Cayman Chemical

US Patent
LigandPNGBDBM190276(US9180116, 28D | US9180116, 28G)
Affinity DataEC50:  0.0162nMT: 2°CAssay Description:1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 uL of reduced serum medium containing 0.5% FBS. Place the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Cayman Chemical

US Patent
LigandPNGBDBM190276(US9180116, 28D | US9180116, 28G)
Affinity DataEC50:  5.68nMT: 2°CAssay Description:1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 uL of reduced serum medium containing 0.5% FBS. Place the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent

TargetProstaglandin E2 receptor EP2 subtype(Human)
Cayman Chemical

US Patent
LigandPNGBDBM190276(US9180116, 28D | US9180116, 28G)
Affinity DataEC50:  65nMT: 2°CAssay Description:1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 ul of reduced serum medium containing 0.5% FBS. Place the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2016
Entry Details
US Patent