BDBM191583 6-(2,6-difluorophenyl)pteridine-2,4,7-triamine (27)

SMILES Nc1nc(N)c2nc(c(N)nc2n1)-c1c(F)cccc1F

InChI Key InChIKey=XBQPWXOKYMXFBA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 191583   

TargetCasein kinase I isoform delta(Human)
Max Planck Institute of Molecular Physiology

LigandPNGBDBM191583(6-(2,6-difluorophenyl)pteridine-2,4,7-triamine (27...)
Affinity DataIC50: 3.57E+4nMpH: 7.5Assay Description:A stock solution of 5 % DMSO (BioReagent for molecular biology, Sigma Aldrich) in water was prepared. The CK1 substrate peptide RRKDLHDDEEDEAMSITA (J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2016
Entry Details Article
PubMed
TargetCasein kinase I isoform epsilon(Human)
Max Planck Institute of Molecular Physiology

LigandPNGBDBM191583(6-(2,6-difluorophenyl)pteridine-2,4,7-triamine (27...)
Affinity DataIC50: 5.15E+4nMpH: 7.5Assay Description:A stock solution of 5 % DMSO (BioReagent for molecular biology, Sigma Aldrich) in water was prepared. The CK1 substrate peptide RRKDLHDDEEDEAMSITA (J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2016
Entry Details Article
PubMed