BDBM191588 6-(thiophen-2-yl)pteridine-2,4,7-triamine (32)

SMILES Nc1nc(N)c2nc(-c3cccs3)c(N)nc2n1

InChI Key InChIKey=HXRKNLICUPWYLM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 191588   

TargetCasein kinase I isoform epsilon(Human)
Max Planck Institute of Molecular Physiology

LigandPNGBDBM191588(6-(thiophen-2-yl)pteridine-2,4,7-triamine (32))
Affinity DataIC50: 8.10E+3nMpH: 7.5Assay Description:A stock solution of 5 % DMSO (BioReagent for molecular biology, Sigma Aldrich) in water was prepared. The CK1 substrate peptide RRKDLHDDEEDEAMSITA (J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2016
Entry Details Article
PubMed
TargetCasein kinase I isoform alpha(Human)
Max Planck Institute of Molecular Physiology

LigandPNGBDBM191588(6-(thiophen-2-yl)pteridine-2,4,7-triamine (32))
Affinity DataIC50: 1.42E+4nMAssay Description:Single-point measurements analyses and subsequent dose-dependent investigations of selected pteridine derivatives for inhibition of CK1α were pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2016
Entry Details Article
PubMed
TargetCasein kinase I isoform delta(Human)
Max Planck Institute of Molecular Physiology

LigandPNGBDBM191588(6-(thiophen-2-yl)pteridine-2,4,7-triamine (32))
Affinity DataIC50: 2.44E+4nMpH: 7.5Assay Description:A stock solution of 5 % DMSO (BioReagent for molecular biology, Sigma Aldrich) in water was prepared. The CK1 substrate peptide RRKDLHDDEEDEAMSITA (J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2016
Entry Details Article
PubMed