BDBM191747 US9187397, 20ag

SMILES COc1cc(\C=C\C(=O)\C=C\c2ccc(OC(C)=O)c(OC)c2)ccc1OC(C)=O

InChI Key InChIKey=GLXJWVWKKACLCW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 191747   

TargetNuclear factor NF-kappa-B p105 subunit(Human)
Stc.Unm

US Patent
LigandPNGBDBM191747(US9187397, 20ag)
Affinity DataIC50: 5.40E+3nMAssay Description:The NF-kB activities of curcumin and analogs were determined by a cellular firefly luciferase assay. This assay utilized a commercially available cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetTranscription factor Jun(Human)
Stc.Unm

US Patent
LigandPNGBDBM191747(US9187397, 20ag)
Affinity DataIC50: 8.30E+3nMAssay Description:Curcumin is a known inhibitor of the AP-1 activation cascade. Therefore, modification of the structure of curcumin could lead to analogs with enhance...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent