BDBM191749 US9187397, 2::US9187397, 6a

SMILES COc1cc(\C=C\C(\O)=C(/C)C(=O)\C=C\c2ccc(O)c(OC)c2)ccc1O

InChI Key InChIKey=MPDFPJQWQLJNLM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 191749   

TargetTranscription factor Jun(Human)
Stc.Unm

US Patent
LigandPNGBDBM191749(US9187397, 6a | US9187397, 2)
Affinity DataIC50: 6.00E+3nMAssay Description:Curcumin is a known inhibitor of the AP-1 activation cascade. Therefore, modification of the structure of curcumin could lead to analogs with enhance...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetNuclear factor NF-kappa-B p105 subunit(Human)
Stc.Unm

US Patent
LigandPNGBDBM191749(US9187397, 6a | US9187397, 2)
Affinity DataIC50: 6.70E+3nMAssay Description:The NF-kB activities of curcumin and analogs were determined by a cellular firefly luciferase assay. This assay utilized a commercially available cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetNuclear factor NF-kappa-B p105 subunit(Human)
Stc.Unm

US Patent
LigandPNGBDBM191749(US9187397, 6a | US9187397, 2)
Affinity DataIC50: 6.70E+3nMAssay Description:The NF-kB activities of curcumin and analogs were determined by a cellular firefly luciferase assay. This assay utilized a commercially available cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent