BDBM19200 (S)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4aH,5H,6H,7H,8H-cyclohexa[f]indazol-5-yl](4-fluorophenyl)methanol::BMCL173354 benzo[f]indazole, 7::N-Arylpyrazolo[3,2-c]-Based Ligand, 20

SMILES [H][C@@]1(CCCC2=Cc3c(C[C@]12C)cnn3-c1ccc(F)cc1)[C@H](O)c1ccc(F)cc1

InChI Key InChIKey=LMWKGVHGBOZNCF-UHFFFAOYSA-N

Data  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 19200   

TargetGlucocorticoid receptor(Human)
Merck Research Laboratories

LigandPNGBDBM19200(BMCL173354 benzo[f]indazole, 7 | (S)-[(4aR,5S)-1-(...)
Affinity DataIC50: 20.4nM EC50:  15.5nMpH: 7.5 T: 2°CAssay Description:The IC50s were determined by incubating the receptors with radiolabeled dexamethasone in the presence of full log scale concentrations (10-11 M to 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2007
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Merck Research Laboratories

LigandPNGBDBM19200(BMCL173354 benzo[f]indazole, 7 | (S)-[(4aR,5S)-1-(...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2007
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Rat)
Merck Research Laboratories

LigandPNGBDBM19200(BMCL173354 benzo[f]indazole, 7 | (S)-[(4aR,5S)-1-(...)
Affinity DataIC50: 5.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2007
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Merck Research Laboratories

LigandPNGBDBM19200(BMCL173354 benzo[f]indazole, 7 | (S)-[(4aR,5S)-1-(...)
Affinity DataIC50: 10.4nM EC50:  16.5nMpH: 7.5 T: 2°CAssay Description:The IC50s were determined by incubating the receptors with radiolabeled dexamethasone in the presence of full log scale concentrations (10-11 M to 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2007
Entry Details Article
PubMed