BDBM192004 Isoquinolin-1(2H)-ones, 4b

SMILES Cc1ccc2c(n1)C(O)CCNC2=O

InChI Key InChIKey=OGPHYMSKYYNFCU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 192004   

TargetAcetylcholinesterase(Electric eel)
Universidade De Evora

LigandPNGBDBM192004(Isoquinolin-1(2H)-ones, 4b)
Affinity DataIC50: 1.50E+6nMAssay Description:The inhibition assay of these compounds for AChE (electrophorus electricus) and BuChE (equine serum) were determined by the spectroscopic method desc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Universidade De Evora

LigandPNGBDBM192004(Isoquinolin-1(2H)-ones, 4b)
Affinity DataIC50: 1.50E+6nMAssay Description:The in vitro BuChE assay was performed similarly to the method described above. A standard enzyme activity curve was drawn for each enzyme using seve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2016
Entry Details Article
PubMed