BDBM192678 1-(4-(3-chlorophenyl)piperazin-1-yl)-3-(6-methoxy-3,4-dihydroquinolin-1(2H)-yl)propan-1-one (6j)

SMILES COc1ccc2N(CCC(=O)N3CCN(CC3)c3cccc(Cl)c3)CCCc2c1

InChI Key InChIKey=IBSWJWMUUPNQCB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 192678   

TargetGag-Pol polyprotein(HIV-1)
Birla Institute of Technology

LigandPNGBDBM192678(1-(4-(3-chlorophenyl)piperazin-1-yl)-3-(6-methoxy-...)
Affinity DataIC50: 1.86E+4nMAssay Description:The reaction mixture was set with template primer complex, RT enzyme and dNTPs in a lysis buffer with or without inhibitors. The reaction mixture was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2016
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Wuhan University of Technology

Curated by ChEMBL
LigandPNGBDBM192678(1-(4-(3-chlorophenyl)piperazin-1-yl)-3-(6-methoxy-...)
Affinity DataIC50: 1.86E+4nMAssay Description:Inhibition of HIV-1 reverse transcriptase after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed