BDBM192688 7-(4-((6-Chloro-2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)amino)phenoxy)-4-methyl-2H-chromen-2-one (8e)

SMILES Cc1cc(=O)oc2cc(Oc3ccc(Nc4c5CCCc5nc5cc(Cl)ccc45)cc3)ccc12

InChI Key InChIKey=YHGBOIWTNXFNCE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 192688   

TargetBeta-secretase 1(Human)
Tehran University of Medical Sciences

LigandPNGBDBM192688(7-(4-((6-Chloro-2,3-dihydro-1H-cyclopenta[b]quinol...)
Affinity DataIC50: 7.99E+3nMpH: 8.0Assay Description:In vitro AChEI activity was performed based on the modified Ellman's methodas previously reported by our group using a 96-well plate reader (BioTek E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Tehran University of Medical Sciences

LigandPNGBDBM192688(7-(4-((6-Chloro-2,3-dihydro-1H-cyclopenta[b]quinol...)
Affinity DataIC50: 1.62E+4nMpH: 8.0Assay Description:In vitro AChEI activity was performed based on the modified Ellman's methodas previously reported by our group using a 96-well plate reader (BioTek E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Tehran University of Medical Sciences

LigandPNGBDBM192688(7-(4-((6-Chloro-2,3-dihydro-1H-cyclopenta[b]quinol...)
Affinity DataIC50: 1.00E+5nMpH: 8.0Assay Description:In vitro AChEI activity was performed based on the modified Ellman's methodas previously reported by our group using a 96-well plate reader (BioTek E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2016
Entry Details Article
PubMed