BDBM19269 Acridone-Based Inhibitor, 8a::N-tert-butyl-9-oxo-9,10-dihydroacridine-3-carboxamide

SMILES CC(C)(C)NC(=O)c1ccc2c(c1)[nH]c1ccccc1c2=O

InChI Key InChIKey=UBNPBAOYSKCJKM-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 19269   

TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb

LigandPNGBDBM19269(N-tert-butyl-9-oxo-9,10-dihydroacridine-3-carboxam...)
Affinity DataIC50: 59nM EC50:  3.30E+3nMpH: 8.0 T: 2°CAssay Description:Inhibition assays were performed using recombinant human IMPDH type 2 and varying concentrations of inhibitor. The production of NADH was monitored b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2007
Entry Details Article
PubMed