BDBM193085 US9193726, 73

SMILES C[C@H]1Cn2c(ccc(-n3cnc(C)c3)c2=O)C(=O)N1C[C@H]1CC[C@H](O1)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=JCSBOEWGZOIJQZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 193085   

TargetPresenilin-1(Human)
Pfizer

US Patent
LigandPNGBDBM193085(US9193726, 73)
Affinity DataIC50: 19.8nMT: 2°CAssay Description:The ability of compounds to modulate production of amyloid beta protein Abeta(1-42) was determined using human WT-APP overexpressing CHO cells. Cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2016
Entry Details
Go to US Patent