BDBM193824 8-Methoxy-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-2-oxo-2H-chromene-3-carboxamide (9d)

SMILES COc1cccc2cc(C(=O)Nc3ccc(CN4CCN(C)CC4)c(c3)C(F)(F)F)c(=O)oc12

InChI Key InChIKey=PKUGBAMRBGKIMO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 193824   

TargetAcetylcholinesterase(Human)
Shenyang Pharmaceutical University

LigandPNGBDBM193824(8-Methoxy-N-(4-((4-methylpiperazin-1-yl)methyl)-3-...)
Affinity DataIC50: 1.45E+3nMpH: 8.0Assay Description:The reaction mixture was consisted of 100 µL of the total volume. To the solution of PBS (pH 8.0, 30 µL) consisted of KH2PO4 and K2HPO4 in 96-well pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2016
Entry Details Article
PubMed