BDBM193917 US9199981, F7

SMILES [#6]-[#8]\[#7]=[#6]-1/[#6]-[#6](-[#6]-1)-c1nc(no1)-c1ccc(-[#6])c(-[#7]-[#6](=O)-c2cnc3ccccn23)c1

InChI Key InChIKey=VGHCTRYXVVEDTB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 193917   

TargetMast/stem cell growth factor receptor Kit(Human)
Novartis

US Patent
LigandPNGBDBM193917(US9199981, F7)
Affinity DataIC50: 15nMAssay Description:The compounds was tested for inhibition of SCF dependent proliferation using human Mo7e cells which endogenously express c-kit in a 384 well format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
Go to US Patent