BDBM193923 US9199981, F13::US9199981, F92

SMILES Cc1ccc(cc1NC(=O)c1cnc2ccccn12)-c1noc(n1)C1CC(F)(F)C1

InChI Key InChIKey=YYJQXSJQDPOQPK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 193923   

TargetMast/stem cell growth factor receptor Kit(Human)
Novartis

US Patent
LigandPNGBDBM193923(US9199981, F92 | US9199981, F13)
Affinity DataIC50: 7nMAssay Description:The compounds was tested for inhibition of SCF dependent proliferation using human Mo7e cells which endogenously express c-kit in a 384 well format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
Go to US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Novartis

US Patent
LigandPNGBDBM193923(US9199981, F92 | US9199981, F13)
Affinity DataIC50: 35nMAssay Description:The compounds was tested for inhibition of SCF dependent proliferation using human Mo7e cells which endogenously express c-kit in a 384 well format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
Go to US Patent