BDBM193953 US9199981, F44

SMILES Cc1ccc(cc1NC(=O)c1cnc2ccc(cn12)-c1cnn(CC(C)(C)O)c1)-c1noc(n1)C1CC(F)(F)C1

InChI Key InChIKey=LSWXHHBJJIGZTD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 193953   

TargetMast/stem cell growth factor receptor Kit(Human)
Novartis

US Patent
LigandPNGBDBM193953(US9199981, F44)
Affinity DataIC50: 6nMAssay Description:The compounds was tested for inhibition of SCF dependent proliferation using human Mo7e cells which endogenously express c-kit in a 384 well format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
Go to US Patent