BDBM193978 US9199981, F69::US9199981, F80

SMILES Cc1ccn2c(cnc2c1)C(=O)Nc1cc(ccc1C)-c1noc(n1)C1CC(F)(F)C1

InChI Key InChIKey=PZQWOZMFFXZLHP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 193978   

TargetMast/stem cell growth factor receptor Kit(Human)
Novartis

US Patent
LigandPNGBDBM193978(US9199981, F80 | US9199981, F69)
Affinity DataIC50: 20nMAssay Description:The compounds was tested for inhibition of SCF dependent proliferation using human Mo7e cells which endogenously express c-kit in a 384 well format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
Go to US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Novartis

US Patent
LigandPNGBDBM193978(US9199981, F80 | US9199981, F69)
Affinity DataIC50: 19nMAssay Description:The compounds was tested for inhibition of SCF dependent proliferation using human Mo7e cells which endogenously express c-kit in a 384 well format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
Go to US Patent