BDBM194084 US9199981, F19

SMILES CO[C@H]1C[C@H](C1)c1nc(no1)-c1ccc(C)c(NC(=O)c2cnc3ccccn23)c1

InChI Key InChIKey=MKRHTMICEQFIHC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 194084   

TargetMast/stem cell growth factor receptor Kit(Human)
Novartis

US Patent
LigandPNGBDBM194084(US9199981, F19)
Affinity DataIC50: 9nMAssay Description:The compounds was tested for inhibition of SCF dependent proliferation using human Mo7e cells which endogenously express c-kit in a 384 well format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
Go to US Patent