BDBM19421 4-{[(3,4-dimethoxyphenyl)amino]methyl}-N-[2-hydroxy-5-(thiophen-2-yl)phenyl]benzamide::benzamide-type inhibitor, 17

SMILES COc1ccc(NCc2ccc(cc2)C(=O)Nc2cc(ccc2O)-c2cccs2)cc1OC

InChI Key InChIKey=QMNQZAGWTHTDTF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 19421   

TargetHistone deacetylase 1(Human)
Methylgene

LigandPNGBDBM19421(4-{[(3,4-dimethoxyphenyl)amino]methyl}-N-[2-hydrox...)
Affinity DataIC50: 40nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2007
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Methylgene

LigandPNGBDBM19421(4-{[(3,4-dimethoxyphenyl)amino]methyl}-N-[2-hydrox...)
Affinity DataIC50: 60nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2007
Entry Details Article
PubMed