BDBM194221 US9200001, 137

SMILES Cc1nc(C)n(n1)-c1cc(nc(OCC2(C)CC2)n1)[C@@H]1C[C@H]1c1nc2ccccc2n1C

InChI Key InChIKey=HOLSBQIXIHIHJA-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 194221   

TargetIsoform PDE10A2 of cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (PDE10A2)(Human)
Merck Sharp & Dohme

US Patent

LigandBDBM194221(US9200001, 137)Copy SMILESCopy InChI

Affinity DataKi:  0.840nMAssay Description:In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exper...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
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Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/27/2016
Entry Details
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