BDBM19457 4-(2-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-5,7-bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl)phenol::Pyrazolo[1,5-a]pyrimidine, 12c

SMILES Oc1ccc(cc1)-c1c(nn2c(cc(nc12)C(F)(F)F)C(F)(F)F)-c1ccc(OCCN2CCCCC2)cc1

InChI Key InChIKey=YGODQTYHFUSOPS-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 19457   

TargetEstrogen receptor beta(Human)
University of Illinois At Urbana-Champaign

LigandPNGBDBM19457(4-(2-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-5,7-bis(...)
Affinity DataKi:  192nM ΔG°:  -8.39kcal/molepH: 7.5 T: 2°CAssay Description:Relative binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer, and purified full-length human ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2007
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Urbana-Champaign

LigandPNGBDBM19457(4-(2-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-5,7-bis(...)
Affinity DataKi:  266nM ΔG°:  -8.21kcal/molepH: 7.5 T: 2°CAssay Description:Relative binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer, and purified full-length human ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2007
Entry Details Article
PubMed