BDBM19549 (2S)-3-cyclohexyl-N-{2-[(4-methoxyphenyl)amino]ethyl}-2-[(3-methylphenyl)formamido]propanamide::arylaminoethyl amide, 5c

SMILES COc1ccc(NCCNC(=O)[C@H](CC2CCCCC2)NC(=O)c2cccc(C)c2)cc1

InChI Key InChIKey=QAEDPWRNBZNYSA-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19549   

TargetProcathepsin L(Human)
Gnf

LigandPNGBDBM19549((2S)-3-cyclohexyl-N-{2-[(4-methoxyphenyl)amino]eth...)
Affinity DataKi:  4.60nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin S(Human)
Gnf

LigandPNGBDBM19549((2S)-3-cyclohexyl-N-{2-[(4-methoxyphenyl)amino]eth...)
Affinity DataKi:  9.70nM ΔG°:  -11.4kcal/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin K(Human)
Gnf

LigandPNGBDBM19549((2S)-3-cyclohexyl-N-{2-[(4-methoxyphenyl)amino]eth...)
Affinity DataKi:  205nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed