BDBM19579 (2S)-2-{[1-(5-bromopyrimidin-2-yl)piperidin-3-yl]formamido}-3-cyclohexyl-N-{2-[(4-methoxyphenyl)amino]ethyl}propanamide::arylaminoethyl amide, 17

SMILES COc1ccc(NCCNC(=O)[C@H](CC2CCCCC2)NC(=O)C2CCCN(C2)c2ncc(Br)cn2)cc1

InChI Key InChIKey=ILOMOYYBNFSCRF-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19579   

TargetCathepsin S(Human)
Gnf

LigandPNGBDBM19579((2S)-2-{[1-(5-bromopyrimidin-2-yl)piperidin-3-yl]f...)
Affinity DataKi:  49nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Gnf

LigandPNGBDBM19579((2S)-2-{[1-(5-bromopyrimidin-2-yl)piperidin-3-yl]f...)
Affinity DataKi:  1.30E+3nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin K(Human)
Gnf

LigandPNGBDBM19579((2S)-2-{[1-(5-bromopyrimidin-2-yl)piperidin-3-yl]f...)
Affinity DataKi: >1.00E+5nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed