BDBM19587 (2S)-4-methyl-2-[(3-methylphenyl)formamido]-N-(2-{[4-(trifluoromethoxy)phenyl]amino}ethyl)pentanamide::arylaminoethyl amide, 3c

SMILES CC(C)C[C@H](NC(=O)c1cccc(C)c1)C(=O)NCCNc1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=NOGPDFYAILRYLC-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19587   

TargetCathepsin S(Human)
Gnf

LigandPNGBDBM19587((2S)-4-methyl-2-[(3-methylphenyl)formamido]-N-(2-{...)
Affinity DataKi:  104nM ΔG°:  -9.90kcal/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Gnf

LigandPNGBDBM19587((2S)-4-methyl-2-[(3-methylphenyl)formamido]-N-(2-{...)
Affinity DataKi:  120nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin K(Human)
Gnf

LigandPNGBDBM19587((2S)-4-methyl-2-[(3-methylphenyl)formamido]-N-(2-{...)
Affinity DataKi:  125nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed