BDBM19591 (2S)-N-[2-(5-chloro-2,3-dihydro-1H-indol-1-yl)ethyl]-4-methyl-2-[(3-methylphenyl)formamido]pentanamide::arylaminoethyl amide, 3g

SMILES CC(C)C[C@H](NC(=O)c1cccc(C)c1)C(=O)NCCN1CCc2cc(Cl)ccc12

InChI Key InChIKey=XGEOFLZCNAEENF-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19591   

TargetProcathepsin L(Human)
Gnf

LigandPNGBDBM19591((2S)-N-[2-(5-chloro-2,3-dihydro-1H-indol-1-yl)ethy...)
Affinity DataKi:  17nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin K(Human)
Gnf

LigandPNGBDBM19591((2S)-N-[2-(5-chloro-2,3-dihydro-1H-indol-1-yl)ethy...)
Affinity DataKi:  139nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin S(Human)
Gnf

LigandPNGBDBM19591((2S)-N-[2-(5-chloro-2,3-dihydro-1H-indol-1-yl)ethy...)
Affinity DataKi:  196nM ΔG°:  -9.51kcal/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed