BDBM19601 (2S)-4-cyclohexyl-N-[(2R)-1-(5-fluoro-2,3-dihydro-1H-indol-1-yl)-3-hydroxypropan-2-yl]-2-[(3-methoxyphenyl)formamido]butanamide::arylaminoethyl amide, 8i

SMILES COc1cccc(c1)C(=O)N[C@@H](CCC1CCCCC1)C(=O)N[C@@H](CO)CN1CCc2cc(F)ccc12

InChI Key InChIKey=MVXHEBDPHVJIEJ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19601   

TargetCathepsin S(Human)
Gnf

LigandPNGBDBM19601((2S)-4-cyclohexyl-N-[(2R)-1-(5-fluoro-2,3-dihydro-...)
Affinity DataKi:  50nM ΔG°:  -10.4kcal/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Gnf

LigandPNGBDBM19601((2S)-4-cyclohexyl-N-[(2R)-1-(5-fluoro-2,3-dihydro-...)
Affinity DataKi:  1.55E+4nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin K(Human)
Gnf

LigandPNGBDBM19601((2S)-4-cyclohexyl-N-[(2R)-1-(5-fluoro-2,3-dihydro-...)
Affinity DataKi: >1.00E+5nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed