BDBM19701 (2S)-3-cyclohexyl-2-{[5-(3-fluorophenyl)furan-2-yl]formamido}-N-(2-{[4-(trifluoromethoxy)phenyl]amino}ethyl)propanamide::arylaminoethyl amide deriv. 15

SMILES Fc1cccc(c1)-c1ccc(o1)C(=O)N[C@@H](CC1CCCCC1)C(=O)NCCNc1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=QTNUFQXBWVAUMR-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19701   

TargetCathepsin S(Human)
Gnf

LigandPNGBDBM19701((2S)-3-cyclohexyl-2-{[5-(3-fluorophenyl)furan-2-yl...)
Affinity DataKi:  34nM ΔG°:  -10.6kcal/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Gnf

LigandPNGBDBM19701((2S)-3-cyclohexyl-2-{[5-(3-fluorophenyl)furan-2-yl...)
Affinity DataKi:  4.08E+3nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin K(Human)
Gnf

LigandPNGBDBM19701((2S)-3-cyclohexyl-2-{[5-(3-fluorophenyl)furan-2-yl...)
Affinity DataKi:  1.17E+4nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed