BDBM19703 (2S)-3-cyclohexyl-2-(furan-2-ylformamido)-N-(2-{[4-(trifluoromethoxy)phenyl]amino}ethyl)propanamide::arylaminoethyl amide deriv. 17

SMILES FC(F)(F)Oc1ccc(NCCNC(=O)[C@H](CC2CCCCC2)NC(=O)c2ccco2)cc1

InChI Key InChIKey=ICZBEHKZUOAGHK-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19703   

TargetCathepsin S(Human)
Gnf

LigandPNGBDBM19703((2S)-3-cyclohexyl-2-(furan-2-ylformamido)-N-(2-{[4...)
Affinity DataKi:  47nM ΔG°:  -10.4kcal/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Gnf

LigandPNGBDBM19703((2S)-3-cyclohexyl-2-(furan-2-ylformamido)-N-(2-{[4...)
Affinity DataKi:  1.15E+3nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin K(Human)
Gnf

LigandPNGBDBM19703((2S)-3-cyclohexyl-2-(furan-2-ylformamido)-N-(2-{[4...)
Affinity DataKi:  8.81E+3nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed