BDBM197353 US9216962, CFH381-B

SMILES Cc1csc(n1)-c1nc(C(=O)NCCCCC(=O)NO)c(s1)C1CC1

InChI Key InChIKey=XBZQADSWPXBGTG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 197353   

TargetHistone deacetylase 1(Human)
Shanghai Puyi Chemical

US Patent
LigandPNGBDBM197353(US9216962, CFH381-B)
Affinity DataIC50: 50nMAssay Description:Enzyme activity of HDAC1,3 is determined using the substrate Ac-Lys-Tyr-Lys(Ac)-AMC while the enzyme activity of HDAC6 is assayed using the substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent

TargetHistone deacetylase 3(Human)
Shanghai Puyi Chemical

US Patent
LigandPNGBDBM197353(US9216962, CFH381-B)
Affinity DataIC50: 60nMAssay Description:Enzyme activity of HDAC1,3 is determined using the substrate Ac-Lys-Tyr-Lys(Ac)-AMC while the enzyme activity of HDAC6 is assayed using the substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Shanghai Puyi Chemical

US Patent
LigandPNGBDBM197353(US9216962, CFH381-B)
Affinity DataIC50: 92nMAssay Description:Enzyme activity of HDAC1,3 is determined using the substrate Ac-Lys-Tyr-Lys(Ac)-AMC while the enzyme activity of HDAC6 is assayed using the substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent