BDBM197719 US9216985, 2A

SMILES Fc1cccc2nc([C@H](CC(F)(F)F)Nc3ncnc4[nH]cnc34)n(-c3ccccc3)c(=O)c12

InChI Key InChIKey=IVSMCBIKTGTBSI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 197719   

LigandPNGBDBM197719(US9216985, 2A)
Affinity DataIC50: 80nMAssay Description:The ability of the compounds of the present invention to inhibit the activity of four PI3K isoforms, PI3Kα, PI3Kβ, PI3Kγ, and PI3K&d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent

LigandPNGBDBM197719(US9216985, 2A)
Affinity DataIC50: 1.80E+3nMAssay Description:The ability of the compounds of the present invention to inhibit the activity of four PI3K isoforms, PI3Kα, PI3Kβ, PI3Kγ, and PI3K&d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent

LigandPNGBDBM197719(US9216985, 2A)
Affinity DataIC50: 3.90E+3nMAssay Description:The ability of the compounds of the present invention to inhibit the activity of four PI3K isoforms, PI3Kα, PI3Kβ, PI3Kγ, and PI3K&d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent