BDBM198130 Ethyl 4-(1,3-diphenyl-1H-Pyrazol-4-yl)-2-oxo-6-(pyridin-3-yl)cyclohex-3-enecarboxylate (5a)

SMILES CCOC(=O)C1C(CC(=CC1=O)c1cn(nc1-c1ccccc1)-c1ccccc1)c1cccnc1

InChI Key InChIKey=HKQYXLOKDIPNJY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 198130   

TargetDNA topoisomerase 2-alpha(Human)
Jamia Millia Islamia (A Central University)

LigandPNGBDBM198130(Ethyl 4-(1,3-diphenyl-1H-Pyrazol-4-yl)-2-oxo-6-(py...)
Affinity DataIC50: 2.22E+5nMpH: 7.9Assay Description:Relaxation of negatively supercoiled plasmid DNA by human topoisomerase IIα was assayed in 20 µL of reaction buffer (10 mM Tris-HCl, pH 7.9, 150...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed