BDBM198161 2-(5-Acetyl-4-(4-bromophenyl)-6-methyl-1,4-dihydropyrimidin-2-ylamino)-N-(4-chlorophenyl) acetamide (4g)::BDBM198169

SMILES CC(=O)C1=C(C)NC(Nc2cc(Cl)ccc2CC(N)=O)=NC1c1ccc(Br)cc1

InChI Key InChIKey=ORSKIWCVSKOOQV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 198161   

TargetAcetylcholinesterase(Electric eel)
Hazara University

LigandPNGBDBM198161(2-(5-Acetyl-4-(4-bromophenyl)-6-methyl-1,4-dihydro...)
Affinity DataIC50: 2.01E+3nMpH: 8.0Assay Description:The synthesized compounds (each separately) were dissolved in a mixture of DMSO (1 ml) and methanol (9 ml) and then diluted in KH2PO4/K2HPO4 buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Hazara University

LigandPNGBDBM198161(2-(5-Acetyl-4-(4-bromophenyl)-6-methyl-1,4-dihydro...)
Affinity DataIC50: 4.96E+3nMpH: 8.0Assay Description:The synthesized compounds (each separately) were dissolved in a mixture of DMSO (1 ml) and methanol (9 ml) and then diluted in KH2PO4/K2HPO4 buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Hazara University

LigandPNGBDBM198161(2-(5-Acetyl-4-(4-bromophenyl)-6-methyl-1,4-dihydro...)
Affinity DataIC50: 1.68E+4nMpH: 8.0Assay Description:The synthesized compounds (each separately) were dissolved in a mixture of DMSO (1 ml) and methanol (9 ml) and then diluted in KH2PO4/K2HPO4 buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Hazara University

LigandPNGBDBM198161(2-(5-Acetyl-4-(4-bromophenyl)-6-methyl-1,4-dihydro...)
Affinity DataIC50: 3.07E+4nMpH: 8.0Assay Description:The synthesized compounds (each separately) were dissolved in a mixture of DMSO (1 ml) and methanol (9 ml) and then diluted in KH2PO4/K2HPO4 buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed