BDBM198191 N1-hydroxy-N4-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)terephthalamide (7b)

SMILES CC1(C)CCC(C)(C)c2cc(NC(=O)c3ccc(cc3)C(=O)NO)ccc12

InChI Key InChIKey=WSHCLQVEVLKKKX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 198191   

TargetHistone deacetylase 8(Human)
Shandong University

LigandPNGBDBM198191(N1-hydroxy-N4-(5,5,8,8-tetramethyl-5,6,7,8-tetrahy...)
Affinity DataIC50: 4.30E+3nMAssay Description:Briefly, the HDAC8 enzyme was diluted 20 times. Then, 10 μL of HDAC8 solution was mixed with compounds at various concentrations (50 μL). T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Shandong University

LigandPNGBDBM198191(N1-hydroxy-N4-(5,5,8,8-tetramethyl-5,6,7,8-tetrahy...)
Affinity DataIC50: 1.00E+5nMpH: 7.2Assay Description:Briefly, the assay was performed in 96-well plates in 50 mm PBS, pH 7.2 as the assay buffer, at 37 °C. The APN solution was mixed with compounds at v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed