BDBM199168 1-(3-(2H-1,2,3-triazol-2-yl)phenyl)-N-6-((1R,2R)-2-aminocyclohexyl)-1H-pyrazolo[3,4-d]pyrimidine-3,6-diamine (5d)

SMILES N[C@@H]1CCCCC1Nc1ncc2c(N)nn(-c3cccc(c3)-n3nccn3)c2n1

InChI Key InChIKey=YIVRLLBHPXNTHK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 199168   

TargetTyrosine-protein kinase SYK(Human)
Jilin University

LigandPNGBDBM199168(1-(3-(2H-1,2,3-triazol-2-yl)phenyl)-N-6-((1R,2R)-2...)
Affinity DataIC50: 938nMpH: 7.5 T: 2°CAssay Description:Briefly, 10 μL per well reactions contained ATP concentration at 25 μm for Syk,2 μm Tyr2 peptide substrate in 50 mm HEPES (PH 7.5), 0....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2016
Entry Details Article
PubMed