BDBM199891 US9226922, 528

SMILES O[C@@H]1CCOc2ccccc2[C@@H]1NC(=O)Nc1cc2[nH]nc(OCC(F)F)c2cn1

InChI Key InChIKey=CEUPUQGSPUWBFD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 199891   

TargetMitogen-activated protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM199891(US9226922, 528)
Affinity DataIC50: 0.600nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each compound was dete...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
Go to US Patent