BDBM201551 (E)-2-[2-(4-Methyl-6-pyrrolidin-1-yl-pyrimidin-2-yl)-vinyl]-quinoline::US9540384, 1

SMILES Cc1cc(nc(n1)/C=C/c2ccc3ccccc3n2)N4CCCC4

InChI Key InChIKey=WQNHXIPMGCIKNP-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 201551   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Hoffmann-La Roche

US Patent

LigandBDBM201551((E)-2-[2-(4-Methyl-6-pyrrolidin-1-yl-pyrimidin-2-y...)Copy SMILESCopy InChI

Affinity DataIC50: 530nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 .mu.l contained 20 mM HEPES pH=7.5/10 mM M...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In Depth
Date in BDB:
8/7/2018
Entry Details
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