BDBM201594 2-(2-(1-methyl-4-phenyl-1h-imidazol-2-yl)ethyl)-6-(pyrrolidin-1-yl)pyridine::Roche-Dataset for PDE10A, Compound 233::US9540384, 6

SMILES Cn1cc(nc1CCc1cccc(n1)N1CCCC1)-c1ccccc1

InChI Key InChIKey=FXZPXKLWRLYOAR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 201594   

LigandPNGBDBM201594(2-(2-(1-methyl-4-phenyl-1h-imidazol-2-yl)ethyl)-6-...)
Affinity DataIC50: 1.84E+3nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 .mu.l contained 20 mM HEPES pH=7.5/10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
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LigandPNGBDBM201594(2-(2-(1-methyl-4-phenyl-1h-imidazol-2-yl)ethyl)-6-...)
Affinity DataIC50: 1.84E+3nMAssay Description:Human PDE10A IC50 values were determined by using purified enzyme (Biomol cat. # SE-534) in a scintillation proximity assay (SPA) in 96 well plates (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details Article
PubMed