BDBM201606 2-(2-(1-methyl-4-phenyl-1h-imidazol-2-yl)ethyl)-6-(pyrazolidin-1-yl)pyrazine hydrochloride::Roche-Dataset for PDE10A, Compound 501::US9540384, 14

SMILES Cn1cc(nc1CCc1cncc(n1)N1CCCN1)-c1ccccc1

InChI Key InChIKey=MYSHCIVSKBYCKN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 201606   

LigandPNGBDBM201606(2-(2-(1-methyl-4-phenyl-1h-imidazol-2-yl)ethyl)-6-...)
Affinity DataIC50: 120nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 .mu.l contained 20 mM HEPES pH=7.5/10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
Go to US Patent

LigandPNGBDBM201606(2-(2-(1-methyl-4-phenyl-1h-imidazol-2-yl)ethyl)-6-...)
Affinity DataIC50: 123nMAssay Description:Human PDE10A IC50 values were determined by using purified enzyme (Biomol cat. # SE-534) in a scintillation proximity assay (SPA) in 96 well plates (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details Article
PubMed