BDBM202032 6-chloro-2-(2-(6-(pyrrolidin-1-yl)pyridin-2-yl)ethyl)quinazolin-4(3h)-one::US9540384, 29

SMILES Clc1ccc2nc(CCc3cccc(n3)N3CCCC3)[nH]c(=O)c2c1

InChI Key InChIKey=HHASCDKICPMBBZ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 202032   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Hoffmann-La Roche

US Patent

LigandBDBM202032(6-chloro-2-(2-(6-(pyrrolidin-1-yl)pyridin-2-yl)eth...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 .mu.l contained 20 mM HEPES pH=7.5/10 mM M...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/7/2018
Entry Details
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