BDBM202058 US9233981, 20

SMILES COc1ccc([C@H]2C[C@H]3CSC(N)=N[C@]3(CO2)c2ccc(F)cc2F)c(F)c1

InChI Key InChIKey=MJAOPMBWEVMUPI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 202058   

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandPNGBDBM202058(US9233981, 20)
Affinity DataIC50: 83nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
Go to US Patent