BDBM202217 (e)-1-(6-(2-(6-chloro-4-(dimethylamino)quinazolin-2-yl)vinyl)pyridin-2-yl)pyrrolidin-2-one::US9540384, 36

SMILES CN(C)c1nc(\C=C\c2cccc(n2)N2CCCC2=O)nc2ccc(Cl)cc12

InChI Key InChIKey=GXMLBRCAFIOGMC-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 202217   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Hoffmann-La Roche

US Patent

LigandBDBM202217((e)-1-(6-(2-(6-chloro-4-(dimethylamino)quinazolin-...)Copy SMILESCopy InChI

Affinity DataIC50: 820nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 .mu.l contained 20 mM HEPES pH=7.5/10 mM M...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/7/2018
Entry Details
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