BDBM202252 (e)-5,7-dimethyl-2-(2-(6-(pyrrolidin-1-yl)pyridin-2-yl)vinyl)[1,2,4]triazolo[1,5-a]pyrimidine::US9540384, 47

SMILES Cc1cc(C)n2nc(\C=C\c3cccc(n3)N3CCCC3)nc2n1

InChI Key InChIKey=KNLVRLGTQKVGIW-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 202252   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Hoffmann-La Roche

US Patent

LigandBDBM202252((e)-5,7-dimethyl-2-(2-(6-(pyrrolidin-1-yl)pyridin-...)Copy SMILESCopy InChI

Affinity DataIC50: 31nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 .mu.l contained 20 mM HEPES pH=7.5/10 mM M...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/7/2018
Entry Details
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