BDBM202279 2,3-dimethyl-5-((6-(pyrrolidin-1-yl)pyridin-2-yl)methoxy)pyrazolo[1,5-a]pyrimidine::US9540384, 53

SMILES Cc1nn2ccc(OCc3cccc(n3)N3CCCC3)nc2c1C

InChI Key InChIKey=UOKLFTOSYFMNAG-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 202279   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Hoffmann-La Roche

US Patent

LigandBDBM202279(2,3-dimethyl-5-((6-(pyrrolidin-1-yl)pyridin-2-yl)m...)Copy SMILESCopy InChI

Affinity DataIC50: 69nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 .mu.l contained 20 mM HEPES pH=7.5/10 mM M...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/7/2018
Entry Details
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