BDBM202555 (E)-3-(3-(1-cyclohexyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl)phenyl)acrylamide (6)

SMILES NC(=O)\C=C\c1cccc(c1)-c1nc2cnc3[nH]ccc3c2n1C1CCCCC1

InChI Key InChIKey=BQGOBAIIYVOGDB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 202555   

TargetTyrosine-protein kinase JAK3(Human)
Eberhard Karls University T£Bingen

Curated by ChEMBL
LigandPNGBDBM202555((E)-3-(3-(1-cyclohexyl-1,6-dihydroimidazo[4,5-d]py...)
Affinity DataIC50: 470nMAssay Description:Inhibition of recombinant human JAK3 (781 to 1124 residues) expressed in baculovirus expression system assessed as reduction in polypeptide substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3 [781-1124](Human)
Eberhard Karls University Tuebingen

LigandPNGBDBM202555((E)-3-(3-(1-cyclohexyl-1,6-dihydroimidazo[4,5-d]py...)
Affinity DataIC50: 470nMAssay Description:In this ELISA-based kinase activity assay, a 96-well assay plate is coated with an artificial polypeptide serving as kinase substrate that contains t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details Article
PubMed